岡部 勝
Necessary documents for ordering:<ol><li>Approval form (<A HREF="https://mus.brc.riken.jp/ja/wp-content/uploads/form/form_6.docx">Japanese</A> / <A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/form_d.docx">English</A>)</li><li>Order form (<A HREF="https://mus.brc.riken.jp/ja/wp-content/uploads/form/form_4.docx">Japanese</A> / <A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/form_b.docx">English</A>)</li><li>Category I MTA: MTA for distribution with RIKEN BRC (<A HREF="https://mus.brc.riken.jp/ja/wp-content/uploads/form/form_5.docx">Japanese</A> / <A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/form_c.docx">English</A>)</li><li>Acceptance of responsibility for living modified organism (<A HREF="https://mus.brc.riken.jp/ja/wp-content/uploads/form/form_7.docx">Japanese</A> / <A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/form_g.docx">English</A>)</li></ol><A HREF="https://egr.biken.osaka-u.ac.jp/achievement/bio_resources" target="_blank">Lab HP</A>
Masaru OKABE
D(6か月以上)
Hhex gene knockout mice. Homozygous mutant mice are embryonic lethal.
true
E. coli Neomycin resistance gene 【クラス1】
D3 [129S2/SvPas]
B6;129-Hhex<tm1Ngu>
B6;129-Hhex<tm1Ngu>
The RECIPIENT of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR. In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Biochem. Biophys. Res. Commun., 276, 1155-1161(2000).RECIPIENT which wants to use the BIOLOGICAL RESOURCE for the purpose other than education or not-for-profit research is requested to enter into a Material Transfer Agreement with Osaka University (https://www.ccb.osaka-u.ac.jp/en/). The RECIPIENT which wants to use the BIOLOGICAL RESOURCE even after five years must obtain a written consent from the DEPOSITOR again.
Hhex遺伝子のノックアウトマウス。hHex遺伝子は肝臓の発生に関与する転写因子であり、ホモマウスは肝臓が発生せず、胎生致死となる。
名古屋大学大学院生命農学研究科 野口民夫先生 (2000)。
Hhex KO, B6-Hhex KO
Heterozygote x Wild-type [C57BL/6NJcl]
Heterozygote x Wild-type [C57BL/6NJcl]
Hhex KO, B6-Hhex KO
Developed by Dr. Tamio Noguchi, Graduate School of Bioagricultural Sciences, Nagoya University in 2000.
RBRC05860
条件を付加する。利用者は事前に寄託者の提供承諾書を得る。<br>研究成果の公表にあたって寄託者の指定する文献を引用する。Biochem. Biophys. Res. Commun., 276, 1155-1161(2000).<br>非営利機関が非営利目的の教育・研究用に用いる場合以外は、大阪大学と別途MTAを締結すること(https://www.ccb.osaka-u.ac.jp/en/)。5年経過後も使用を希望するときは改めて寄託者から承諾を得るものとする。
Developmental Biology Research
D (more than 6 months)